Vacation rentals in Calhoun County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Calhoun County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Orangeburg
4.95 out of 5 average rating, 87 reviews

Cozy, comfy, convenient, cottage!

We think you'll love this peaceful, family friendly cottage. For a price similar to a local hotel, you'll get a newly remodeled 2-bedroom house complete with kitchen and formal dining room located on fenced in lot 🐶 in quiet neighborhood. The master has a king bed with 400 count Egyptian cotton sheets and a bamboo mattress topper. The guest has a queen bed with a sensafoam mattress. There is a new 50” tv and high speed fiber WI-FI. There is also a breakfast bar with your favorite coffee.

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Top guest favorite
Home in Orangeburg
5.0 out of 5 average rating, 22 reviews

Renovated—Spotless Home—Quiet Area Near Food/HBCUs

Escape to this peaceful 2-acre retreat that overlooks Criddle Pond — a lovely 5-acre pond facing the backyard. You’ll enjoy the serene waterfront views. This spacious, modern farmhouse is located at the end of a cul-de-sac. The one-story renovated home offers comfortable rooms and lots of amenities. The home is close to places of interest: — 2-3 minute drive • Dining, groceries, shopping • Orangeburg Recreational Park — 8-10 minute drive • S. C. S. U. and C. U. • Orangeburg Country Club

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Guest favorite
A charming waterfront home is surrounded by trees, featuring a screened porch that provides a view of the yard. Green grass on a gentle slope leads up to the house, with bushes adding a touch of greenery. A dog stands near the porch, complementing the serene setting.
Home in Cameron
4.81 out of 5 average rating, 27 reviews

Fisherman's Dream at Low Falls Landing-Lake Marion

Don't Overlook this Waterfront Property! Fisherman's Dream on Lake Marion and Duck Hunter's Delight! Throw back from the 70's! Put in at Low Falls Landing & then tie on to the property's private dock. This is a 2 bdrm, 2 bth home. Screened porch w/swing & rocking chairs over looks waterfront. Open family rm & kitch. Gather w/friends & family. Large private dock w/ seating and rod holders. Lake Marion, largest lake in SC, catfish, crappy and brim fishing. Dogs welcome, No cats please.

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Guest favorite
A spacious bedroom features a large, elegantly crafted bed adorned with patterned bedding and decorative pillows. Soft lighting is provided by two bedside lamps on matching nightstands. Natural light enters through a window covered by light curtains, contributing to a warm ambiance.
Home in Pinewood
4.94 out of 5 average rating, 97 reviews

Ultimate Hideaway in the pines next to Lake Marion

Discover the hidden secrets of the midlands of South Carolina. Minutes away from fishing Lake Marion, and discovering hidden gems of both SC state and national parks. Surrounded by the serenity of nature, near the Palmetto trail and endless hiking and biking trails. Ramble the scenic byways and back roads of the area and discover our hidden small towns, historic sites and natural wonders. Convenient to visitors of Shaw Air force base and within reasonable distance to the charm of Charleston.

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Superhost
Cabin in St. Matthews
4.76 out of 5 average rating, 206 reviews

A relaxing cabin on private pond. Old Bells Secret

Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!

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Top guest favorite
Home in Orangeburg
5.0 out of 5 average rating, 153 reviews

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

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Top guest favorite
Boat in Cameron
5.0 out of 5 average rating, 14 reviews

Docked Paddlewheel Houseboat| Fishing & Kayaking

Experience a stay on a one-of-a-kind stationary paddlewheel boat on Lake Marion. Once a passenger vessel, this floating retreat blends comfort and charm in a truly unique setting. Wake up to peaceful water views, cast a line from the dock, or sip coffee on the upper deck. Relax by the fire pit, grill on the deck, or take the kayaks out for a sunset paddle. Whether you’re here for a fishing trip, romantic getaway, or peaceful reset, this floating escape promises an unforgettable stay.

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Guest favorite
The exterior of a renovated Cape Cod home is visible, featuring a light-colored façade with dark trim. A brick chimney rises from the sloping roof. A front porch with decorative railing adds charm, while neat landscaping frames the property, enhancing its inviting presence.
Home in Orangeburg
4.92 out of 5 average rating, 50 reviews

Ron's Siesta Airbnb

A beautifully renovated Cape Cod, reminiscent of the late 1940's is located near restaurants, groceries, and the universities; some of which are in walking distance. While located on a main thoroughfare, the home exudes a quiet and peaceful atmosphere. There are two bedrooms, bath, kitchen, eating and dinning area. A warn place to feel welcomed and at home. Universities: SCSU walk 18 min 1.0mil; Claflin University walk 15min. 0.8 mil; The Village Center walk: 3min 0.2mil.

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Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 195 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

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Guest favorite
Home in Orangeburg
5.0 out of 5 average rating, 25 reviews

Furnished 3BR Near MUSC, SC State & Claflin

Relax in comfort at Stamford Haven Retreat! Enjoy a private fenced backyard with patio seating, a zero-gravity massage chair, and a fully stocked kitchen. Wake up to our Keurig coffee bar with coffee, teas, iced tea, creamers, sugar, and honey. Washer/dryer with detergent pods included. Minutes from SCSU, Claflin, MUSC, shopping, and dining—the perfect home away from home with hotel-style comforts and thoughtful amenities for every stay!

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Guest favorite
Home in North
4.93 out of 5 average rating, 15 reviews

Work Crew or Vacation | Gourmet Kitchen | Woods

Work Crew - plenty of parking. or Vacation Welcome to your peaceful retreat on 5.46 acres in North, South Carolina. This spacious 3-bedroom, family-friendly getaway features a gourmet kitchen, dedicated workspace, Roku TVs in every room, and relaxing outdoor amenities—perfect for families, remote workers, or anyone seeking comfort and privacy. ⭑CONTACT US FOR SEASONAL DISCOUNTS⭑

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Top guest favorite
The two-story A-frame home is surrounded by lush greenery, featuring large windows that invite natural light. A spacious deck enhances outdoor living areas, complementing the expansive lawn. A small circular seating area is visible on the grass, offering a peaceful spot for relaxation.
Home in Cameron
4.93 out of 5 average rating, 40 reviews

The Cypress House

Stunning views and peaceful setting directly on Lake Marion. The entire property will be yours to enjoy for the length of your stay. The property can sleep 14 guests in a total of 9 beds, another 3 on the couches, and still have room left for air mattresses to be utilized if you have a larger group. Please reach out if you have any questions!

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Popular amenities for Calhoun County vacation rentals